BDBM373585 1-(4-(Ethyl(methyl)amino)-6-phenylquinazolin-2-yl)-1H-pyrazole-4-carboxylic acid;::US10246442, Example 42::US10975062, Example 42

SMILES CCN(C)c1nc(nc2ccc(cc12)-c1ccccc1)-n1cc(cn1)C(O)=O

InChI Key InChIKey=GNXUCULRWLFJPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 373585   

TargetEgl nine homolog 1 [181-417](Human)
TBA

US Patent
LigandPNGBDBM373585(1-(4-(Ethyl(methyl)amino)-6-phenylquinazolin-2-yl)...)
Affinity DataIC50:  50.1nMAssay Description:The PHD enzymatic assay was performed in 0.5 ml of reaction mixture containing the following: purified PHD2181-417 polypeptide (3 μg), synthetic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetEgl nine homolog 1 [182-426](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM373585(1-(4-(Ethyl(methyl)amino)-6-phenylquinazolin-2-yl)...)
Affinity DataIC50:  50.1nMAssay Description:The PHD enzymatic assay was performed in 0.5 ml of reaction mixture containing the following: purified PHD2181-417 polypeptide (3 μg), synthetic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent