BDBM374094 3-amino-5-(1-(6-(trifluoromethyl)pyridin-2-yl)-1H-indazol-6-yl)benzoic Acid::US10246456, Example 85::US10577367, Example 85

SMILES Nc1cc(cc(c1)-c1ccc2cnn(-c3cccc(n3)C(F)(F)F)c2c1)C(O)=O

InChI Key InChIKey=QCSNHOWMNPUFJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 374094   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM374094(US10246456, Example 85 | 3-amino-5-(1-(6-(trifluor...)
Affinity DataIC50: 100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM374094(US10246456, Example 85 | 3-amino-5-(1-(6-(trifluor...)
Affinity DataIC50: 100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent