BDBM374114 1-(4-methyl-6-(1-(6-methylpyridin-2-yl)-1H-indazol-6-yl)pyridin-2-yl)ethanamine::US10246456, Example 124::US10577367, Example 124

SMILES CC(N)c1cc(C)cc(n1)-c1ccc2cnn(-c3cccc(C)n3)c2c1

InChI Key InChIKey=AHSBSSHRRSSKDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 374114   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM374114(US10246456, Example 124 | 1-(4-methyl-6-(1-(6-meth...)
Affinity DataIC50: 100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM374114(US10246456, Example 124 | 1-(4-methyl-6-(1-(6-meth...)
Affinity DataIC50: 100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2020
Entry Details
US Patent