BDBM374216 (S)-(6-(6-(6-(1-aminoethyl)pyridin-2-yl)-4-(1-methyl-1H-pyrazol-3-yl)-1H-indazol-1-yl)pyridin-2-yl)methanol::US10246456, Example 357

SMILES C[C@H](N)c1cccc(n1)-c1cc(-c2ccn(C)n2)c2cnn(-c3cccc(CO)n3)c2c1

InChI Key InChIKey=RWRHGIHCJNQFRL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374216   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 374216BDBM374216(US10246456, Example 357 | (S)-(6-(6-(6-(1-aminoeth...)
Affinity DataIC50: 100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent