BDBM374494 (S)-(6-(6-(6-(1-aminoethyl)pyridin-2-yl)-1H-indazol-1-yl)pyrazin-2-yl)methanol::US10246456, Example 397::US10577367, Example 397

SMILES C[C@H](N)c1cccc(n1)-c1ccc2cnn(-c3cncc(CO)n3)c2c1

InChI Key InChIKey=QBHQKEWWQAYWIR-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 374494   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 374494BDBM374494(US10246456, Example 397 | (S)-(6-(6-(6-(1-aminoeth...)
Affinity DataIC50: 550nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 374494BDBM374494(US10246456, Example 397 | (S)-(6-(6-(6-(1-aminoeth...)
Affinity DataIC50: 550nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent