BDBM374644 1-(1-(2,4-Dichlorophenyl)ethyl)-6-(3′-fluoro-[1,4′-bipiperidin]-1′-yl)-1H-pyrazolo[3,4-b]pyrazine-3-carboxamide hydrochloride::US10246462, Example 25

SMILES CC(c1ccc(Cl)cc1Cl)n1nc(C(N)=O)c2ncc(nc12)N1CCC(C(F)C1)N1CCCCC1

InChI Key InChIKey=RHVCYIUCDZPACM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374644   

TargetC-C chemokine receptor type 4(Human)
Flx Bio

US Patent
LigandPNGBDBM374644(US10246462, Example 25 | 1-(1-(2,4-Dichlorophenyl)...)
Affinity DataIC50: 300nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent