BDBM3747 N-[(1R)-1-phenylethyl]-5H-pyrimido[5,4-b]indol-4-amine::Pyrimido[5,4-b]indole deriv. 38

SMILES C[C@@H](Nc1ncnc2c3ccccc3[nH]c12)c1ccccc1

InChI Key InChIKey=LITMWRKODNTXFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3747   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3747(N-[(1R)-1-phenylethyl]-5H-pyrimido[5,4-b]indol-4-a...)
Affinity DataIC50: 419nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed