BDBM374802 US10251893, Cpd 6
SMILES COc1ccc2nc(NC(=O)Cc3ccc(cc3)-c3ccnc(C)c3)sc2c1
InChI Key InChIKey=VZUYDLBCAYXKGE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 374802
Affinity DataIC50: 0.5nMAssay Description:Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair