BDBM375606 N-(5-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)-2-(piperazine-1-carbonyl)phenyl)acetamide::US9908886, Example 170

SMILES CC(=O)Nc1cc(ccc1C(=O)N1CCN(CC1)C(=O)OC(C)(C)C)-c1ccc2ncc(-c3ccc(cc3)C#N)n2c1

InChI Key InChIKey=GKMDEAIIWOYQSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 375606   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM375606(US9908886, Example 170 | N-(5-(3-(4-cyanophenyl)im...)
Affinity DataIC50: 100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM375606(US9908886, Example 170 | N-(5-(3-(4-cyanophenyl)im...)
Affinity DataIC50: 100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent