BDBM3757 4-N-(3-bromophenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine::Pyrimido[4,5-b]indole deriv. 48

SMILES Nc1nc(Nc2cccc(Br)c2)c2c(n1)[nH]c1ccccc21

InChI Key InChIKey=NOUNTOCKLNSANP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3757   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3757(4-N-(3-bromophenyl)-9H-pyrimido[4,5-b]indole-2,4-d...)
Affinity DataIC50: 147nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed