BDBM376005 2-fluoro-N-(2-methyl-4- phenyl-1,3-thiazol-5-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 1

SMILES Cc1nc(c(NC(=O)c2ccc(cc2F)C(F)(F)F)s1)-c1ccccc1

InChI Key InChIKey=QIGUYFLVKWLWJC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376005   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 376005BDBM376005(US9914736, Compound 1 | 2-fluoro-N-(2-methyl-4- ph...)
Affinity DataIC50: 780nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
US Patent