BDBM376387 N-(3-(cyclopropylcarbamoyl) benzyl)-6-methyl- 6H-isochromeno [3,4-c]pyridine-8- carboxamide::US9914740, VIII-13

SMILES CC1Oc2cnccc2-c2ccc(cc12)C(=O)NCc1cccc(c1)C(=O)NC1CC1

InChI Key InChIKey=JLFFCWIINHGPAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376387   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376387(US9914740, VIII-13 | N-(3-(cyclopropylcarbamoyl) b...)
Affinity DataIC50: 0.850nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
US Patent