BDBM376617 US9918990, Example 67

SMILES Cn1cc(-c2ccc3c(c2OCC2CCC2)n(CCN2CCN(S(C)(=O)=O)CC2)c(=O)n3C)c2cc[nH]c2c1=O

InChI Key InChIKey=SBOJEZDUTMGDOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376617   

TargetBromodomain-containing protein 2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 376617BDBM376617(US9918990, Example 67)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 376617BDBM376617(US9918990, Example 67)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
US Patent