BDBM376618 US9918990, Example 68

SMILES CN1CCN(CCn2c3c(OCC4CCC4)c(ccc3n(C)c2=O)-c2cn(C)c(=O)c3[nH]ccc23)CC1

InChI Key InChIKey=AAQQNBOLQVTMLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376618   

TargetBromodomain-containing protein 4(Human)
Incyte

US Patent
LigandPNGBDBM376618(US9918990, Example 68)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
US Patent

TargetBromodomain-containing protein 2(Human)
Incyte

US Patent
LigandPNGBDBM376618(US9918990, Example 68)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
US Patent