BDBM376845 (R)-(2-((4-(2-hydroxypropan-2- yl)-5-methyloxazol-2- yl)methyl)piperidin-1-yl)(2- isopropoxypyridin-3- yl)methanone::US9920038, 6

SMILES CC(C)Oc1ncccc1C(=O)N1CCCC[C@@H]1Cc1nc(c(C)o1)C(C)(C)O

InChI Key InChIKey=PXRYFCQUFHLNOH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376845   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376845(US9920038, 6 | (R)-(2-((4-(2-hydroxypropan-2- yl)-...)
Affinity DataIC50: 36nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376845(US9920038, 6 | (R)-(2-((4-(2-hydroxypropan-2- yl)-...)
Affinity DataIC50: 223nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
US Patent