BDBM376858 (R)-(2-cyclopropyl-6- methoxypyridin-3-yl)(2-((4-(2- hydroxypropan-2-yl)-5- methyloxazol-2- yl)methyl)piperidin-1- yl)methanone::US9920038, 19

SMILES COc1ccc(C(=O)N2CCCC[C@@H]2Cc2nc(c(C)o2)C(C)(C)O)c(n1)C1CC1

InChI Key InChIKey=UIXPENHEWIPICY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376858   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376858(US9920038, 19 | (R)-(2-cyclopropyl-6- methoxypyrid...)
Affinity DataIC50: 503nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376858(US9920038, 19 | (R)-(2-cyclopropyl-6- methoxypyrid...)
Affinity DataIC50: 2.31E+3nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
US Patent