BDBM376941 US10329300, Example 29::US11696917, Example 29::US9920060, 29

SMILES CN(C)C(=O)Oc1ccc(NC(=O)c2nn([C@@H]3CCCN(C3)C(=O)C=C)c3ncnc(N)c23)cc1Cl

InChI Key InChIKey=RBDSUTFPAMHZSL-CQSZACIVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 376941   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM376941(US10329300, Example 29 | US11696917, Example 29 | ...)
Affinity DataIC50:  6.5nMAssay Description:For setting the conditions for the method for measuring the in vitro inhibitory activity of a compound against HER2-phosphorylating activity, Profile...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetReceptor tyrosine-protein kinase erbB-2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM376941(US10329300, Example 29 | US11696917, Example 29 | ...)
Affinity DataIC50:  6.5nMAssay Description:For setting the conditions for the method for measuring the in vitro inhibitory activity of a compound against HER2-phosphorylating activity, Profile...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetReceptor tyrosine-protein kinase erbB-2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM376941(US10329300, Example 29 | US11696917, Example 29 | ...)
Affinity DataIC50:  6.5nMAssay Description:For the inhibitory activity measurement of each compound, the compound of the present invention or staurosporine was first serially diluted with dime...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent