BDBM377012 8-(4-Methylsulfonyl-2-methoxyphenyl)-N-[4-(piperidin-4-yl)-2,3-dihydro-1-benzofuran-7-yl]oxazolin-2-amine ::US10259816, Compound 34::US10611770, Compound 34

SMILES COc1cc(ccc1-c1cccc2cnc(Nc3ccc(C4CCNCC4)c4CCOc34)nc12)S(C)(=O)=O

InChI Key InChIKey=GTVLHDASZOHFBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377012   

TargetALK tyrosine kinase receptor(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM377012(US10259816, Compound 34 | 8-(4-Methylsulfonyl-2-me...)
Affinity DataIC50: 14nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM377012(US10259816, Compound 34 | 8-(4-Methylsulfonyl-2-me...)
Affinity DataIC50: 14nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent