BDBM377016 N-[7-(2-methoxyphenyl)-6-methylthieno[3,2-d]pyrimidin-2-yl]-3-(piperidin-4-yl)-1-isopropyl-1-H-pyrazol-5-amine ::US10259816, Compound 42::US10611770, Compound 42

SMILES COc1ccccc1C1=C(C)SC2C=NC(Nc3cc(nn3C(C)C)C3CCNCC3)=NC12

InChI Key InChIKey=OVDDVCHBLXIYHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377016   

TargetALK tyrosine kinase receptor(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM377016(US10259816, Compound 42 | N-[7-(2-methoxyphenyl)-6...)
Affinity DataIC50: 2.70nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM377016(US10259816, Compound 42 | N-[7-(2-methoxyphenyl)-6...)
Affinity DataIC50: 2.70nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent