BDBM377041 US10259818, Example 23::US9944646, Example 23

SMILES CC(c1cc(Cl)c(C)c2CN(CCOc12)c1ncc(s1)C#N)n1nc(C)c2c(N)ncnc12

InChI Key InChIKey=PFBVLXCOCKQXIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377041   

LigandPNGBDBM377041(US10259818, Example 23 | US9944646, Example 23)
Affinity DataIC50: <100nMAssay Description:[γ-33P]ATP (10mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM377041(US10259818, Example 23 | US9944646, Example 23)
Affinity DataIC50: <100nMAssay Description:Lipid kinase substrate, phosphoinositol-4,5-bisphosphate (PIP2), are purchased from Echelon Biosciences (Salt Lake City, Utah). PI3K isoforms α,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent