BDBM377074 US10259818, Example 103::US10259818, Example 56::US9944646, Example 104

SMILES CC(c1cc(Cl)c(C#N)c2CN(C[C@H](C)Oc12)C1CN(CCO)C1)n1nc(C)c2c(N)ncnc12

InChI Key InChIKey=IZCPARMBVZDRHG-CFMCSPIPSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 377074   

LigandPNGBDBM377074(US10259818, Example 103 | US10259818, Example 56 |...)
Affinity DataIC50: <100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM377074(US10259818, Example 103 | US10259818, Example 56 |...)
Affinity DataIC50: <100nMAssay Description:[γ-33P]ATP (10mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM377074(US10259818, Example 103 | US10259818, Example 56 |...)
Affinity DataIC50: <100nMAssay Description:[γ-33P]ATP (10mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM377074(US10259818, Example 103 | US10259818, Example 56 |...)
Affinity DataIC50: <100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent