BDBM377093 1-{1-[7-chloro-6-fluoro-2- methyl-4-(1- propionylazetidin-3-yl)- 2,3,4,5-tetrahydro-1,4- benzoxazepin-9-yl]ethyl}- 3-methyl-1H-pyrazolo[3,4- d]pyrimidin-4-amine::US10259818, Example 76::US9944646, Example 76

SMILES CCC(=O)N1CC(C1)N1CC(C)Oc2c(cc(Cl)c(F)c2C1)C(C)n1nc(C)c2c(N)ncnc12

InChI Key InChIKey=YDYHCMIUVIUELO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377093   

LigandPNGBDBM377093(US9944646, Example 76 | US10259818, Example 76 | 1...)
Affinity DataIC50: 100nMAssay Description:[γ-33P]ATP (10mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent

LigandPNGBDBM377093(US9944646, Example 76 | US10259818, Example 76 | 1...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent