BDBM377644 2-methoxy-4-{[(7-methoxy-2-oxo-1,2-dihydroquinolin-3-::US10266495, Compound I-56

SMILES COc1ccc2cc(CNc3ccc(C#N)c(OC)c3)c(=O)[nH]c2c1

InChI Key InChIKey=AILNNOASKOKXGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 377644   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Forma Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 377644BDBM377644(US10266495, Compound I-56 | 2-methoxy-4-{[(7-metho...)
Affinity DataIC50: 550nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent