BDBM378839 US10266528, Compound 23

SMILES Cc1cc(-c2ccnc3[nH]c(=O)[nH]c23)ccc1CNC(=O)c1nc(C(C)(C)C)no1

InChI Key InChIKey=KAUIANSROGMAFA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378839   

TargetTyrosine-protein kinase BTK(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 378839BDBM378839(US10266528, Compound 23)
Affinity DataIC50: 10nMAssay Description:Briefly, 2.5× stocks of full-length human BTK (08-080) from CarnaBio USA, Inc., Natick, Mass., 1.6×ATP and appropriate kinKDR peptide substrate (FITC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent