BDBM378843 US10266528, Compound 18

SMILES CC1(c2noc(C(=O)NCc3ccc(-c4ccnc5[nH]c(=O)[nH]c45)cc3C(F)(F)F)n2)CC1

InChI Key InChIKey=ITGWLRPJMKSOMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378843   

TargetTyrosine-protein kinase BTK(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 378843BDBM378843(US10266528, Compound 18)
Affinity DataIC50: 10nMAssay Description:Briefly, 2.5× stocks of full-length human BTK (08-080) from CarnaBio USA, Inc., Natick, Mass., 1.6×ATP and appropriate kinKDR peptide substrate (FITC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent