BDBM381510 4-Chloro-3-methyl-1-(2-morpholin- 4-yl-ethyl)-1H-pyrazolo[3,4- b]pyridine-5-carboxylic acid (4- trifluoromethyl-phenyl)-amide::US10272074, Example 344

SMILES Cc1nn(CCN2CCOCC2)c2ncc(C(=O)Nc3ccc(cc3)C(F)(F)F)c(Cl)c12

InChI Key InChIKey=UUCXYXNYCZCHNA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381510   

TargetGlucocorticoid receptor(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381510(4-Chloro-3-methyl-1-(2-morpholin- 4-yl-ethyl)-1H-p...)
Affinity DataIC50: 50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
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Date in BDB:
2/20/2020
Entry Details
US Patent