BDBM381511 4-Chloro-3-methyl-1-(2-morpholin- 4-yl-ethyl)-1H-pyrazolo[3,4- b]pyridine-5-carboxylic acid (4- isopropyl-phenyl)-amide::US10272074, Example 345

SMILES CC(C)c1ccc(NC(=O)c2cnc3n(CCN4CCOCC4)nc(C)c3c2Cl)cc1

InChI Key InChIKey=YICDIBPHRDRNTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381511   

TargetGlucocorticoid receptor(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381511(4-Chloro-3-methyl-1-(2-morpholin- 4-yl-ethyl)-1H-p...)
Affinity DataIC50: 50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent