BDBM382345 US10273259, Example 63::US10711020, Example 63

SMILES OC(=O)[C@H]1CC[C@@](O)(CC1)C(=O)N1CCC2(C1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=TYAAJBCLFWLEPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 382345   

TargetNuclear receptor ROR-gamma(Mouse)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM382345(US10273259, Example 63 | US10711020, Example 63)
Affinity DataIC50: 21nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM382345(US10273259, Example 63 | US10711020, Example 63)
Affinity DataIC50: 21nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2021
Entry Details
US Patent