BDBM382802 US10273259, Example 513::US10273259, Example 522::US10711020, Example 522

SMILES CN1[C@@H](C[C@H](F)C1=O)C(=O)N1CCC2(C1CNc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1cccc(F)c1

InChI Key InChIKey=RXUZMAZHAXJPIV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 382802   

TargetNuclear receptor ROR-gamma(Mouse)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM382802(US10273259, Example 522 | US10273259, Example 513 ...)
Affinity DataIC50: 18nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM382802(US10273259, Example 522 | US10273259, Example 513 ...)
Affinity DataIC50: 18nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM382802(US10273259, Example 522 | US10273259, Example 513 ...)
Affinity DataIC50: 6.56E+3nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Mouse)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM382802(US10273259, Example 522 | US10273259, Example 513 ...)
Affinity DataIC50: 6.56E+3nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent