BDBM383546 2-[6-(1-cyclobutylpiperidine-3-carbonyl)-2-methoxy-1-naphthyl]acetonitrile::US10280149, Example 55

SMILES COc1ccc2cc(ccc2c1CC#N)C(=O)C1CCCN(C1)C1CCC1

InChI Key InChIKey=FYBQNEKPUGASSS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383546   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandPNGBDBM383546(2-[6-(1-cyclobutylpiperidine-3-carbonyl)-2-methoxy...)
Affinity DataIC50:  13.2nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent