BDBM383664 6-(1-(cyclopropylmethyl)piperidine-3-carbonyl)-2-naphthonitrile::US10280149, Example 159

SMILES O=C(C1CCCN(CC2CC2)C1)c1ccc2cc(ccc2c1)C#N

InChI Key InChIKey=AABDPJPJDYYAFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383664   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandPNGBDBM383664(6-(1-(cyclopropylmethyl)piperidine-3-carbonyl)-2-n...)
Affinity DataIC50:  68.8nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent