BDBM384657 US10376513, Example 352::US10646492, Example 349::US11433071, Example 352::US9932341, Example 352

SMILES CCOc1c(cc(Cl)c(C#N)c1[C@H]1CNC(=O)C1)[C@H](C)n1nc(C)c2c(N)ncnc12

InChI Key InChIKey=IIEKNYURGTYVMT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 384657   

LigandPNGBDBM384657(US9932341, Example 352 | US10376513, Example 352 |...)
Affinity DataIC50: 10nMAssay Description:[γ-33P]ATP (10 mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Pt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

LigandPNGBDBM384657(US9932341, Example 352 | US10376513, Example 352 |...)
Affinity DataIC50: 10nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 uL. Inhibitors wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

LigandPNGBDBM384657(US9932341, Example 352 | US10376513, Example 352 |...)
Affinity DataIC50: 10nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
US Patent

LigandPNGBDBM384657(US9932341, Example 352 | US10376513, Example 352 |...)
Affinity DataIC50: 10nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 uL. Inhibitors wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent