BDBM385559 US10287279, Compound 1::US10287279, Compound 20

SMILES CNC1OC(=NC1C#N)c1cccc2ccccc12

InChI Key InChIKey=DOSDTMAEYPWRJB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 385559   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
The Children'S Hospital

US Patent
LigandPNGBDBM385559(US10287279, Compound 1 | US10287279, Compound 20)
Affinity DataIC50: 200nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
The Children'S Hospital

US Patent
LigandPNGBDBM385559(US10287279, Compound 1 | US10287279, Compound 20)
Affinity DataIC50: 200nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
The Children'S Hospital

US Patent
LigandPNGBDBM385559(US10287279, Compound 1 | US10287279, Compound 20)
Affinity DataIC50: 200nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
The Children'S Hospital

US Patent
LigandPNGBDBM385559(US10287279, Compound 1 | US10287279, Compound 20)
Affinity DataIC50: 3.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
US Patent