BDBM386163 US10287305, Example 118::cis-N-ethyl-3-((methylsulfonyl)amino)- 2-(((1-(pyrimidin-2-yl)piperidin-4- yl)oxy)methyl)piperidine-1-carboxamide

SMILES CCNC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@H](CC1)c1ncccn1

InChI Key InChIKey=QOFQUYNHZCCTHH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 386163   

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386163(cis-N-ethyl-3-((methylsulfonyl)amino)- 2-(((1-(pyr...)
Affinity DataEC50:  4.60nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
US Patent