BDBM386432 (1R,3S,5R)-2-(2- (3-acetyl-5-(2- methylpyrimidin- 5-yl)-1H-indazol- 1-yl)acetyl)-N-(6- bromo-4- methoxypyridin- azabicyclo[3.1.0] hexane-3- carboxamide::US10287301, Compound 366::US10822352, Comp No. 366

SMILES COc1cc(Br)nc(NC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(C)=O)c3cc(ccc23)-c2cnc(C)nc2)c1

InChI Key InChIKey=BTPJCWBZYWEALP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 386432   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 386432BDBM386432(US10287301, Compound 366 | (1R,3S,5R)-2-(2- (3-ace...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 386432BDBM386432(US10287301, Compound 366 | (1R,3S,5R)-2-(2- (3-ace...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent