BDBM386840 N-(cis-1-(cyclopropylcarbonyl)-2- (((cis-4- phenylcyclohexyl)oxy)methyl)- piperidin-3-yl)ethanesulfonamide::US10287305, Example 279::US10508083, Example 279::US11292766, Example 279

SMILES CCS(=O)(=O)N[C@H]1CCCN([C@H]1CO[C@H]1CC[C@H](CC1)c1ccccc1)C(=O)C1CC1

InChI Key InChIKey=CDIZBIQDWASGMQ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 386840   

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386840(N-(cis-1-(cyclopropylcarbonyl)-2- (((cis-4- phenyl...)
Affinity DataEC50:  5.20nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386840(N-(cis-1-(cyclopropylcarbonyl)-2- (((cis-4- phenyl...)
Affinity DataEC50:  5.20nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386840(N-(cis-1-(cyclopropylcarbonyl)-2- (((cis-4- phenyl...)
Affinity DataEC50:  5.20nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
US Patent