BDBM387242 US9938274, 7

SMILES CC(C)(O)COc1ccc2c(Oc3ccc(Nc4nccc5[nH]cc(-c6ccccc6)c(=O)c45)cc3F)ccnc2c1

InChI Key InChIKey=DGRCFAYRKDYEMX-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 387242   

TargetHepatocyte growth factor receptor(Human)
Nanjing Natinefy Pharmatech

US Patent
LigandPNGBDBM387242(US9938274, 7)
Affinity DataIC50: 7.40nMAssay Description:A study on inhibition of protein kinases activity at in vitro biochemical levelMaterial and method: kinases such as c-Met, VEGFR-2, Axl and RET, obta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Nanjing Natinefy Pharmatech

US Patent
LigandPNGBDBM387242(US9938274, 7)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of MET (unknown origin) using biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 to 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Nanjing Natinefy Pharmatech

US Patent
LigandPNGBDBM387242(US9938274, 7)
Affinity DataIC50: 10.2nMAssay Description:A study on inhibition of protein kinases activity at in vitro biochemical levelMaterial and method: kinases such as c-Met, VEGFR-2, Axl and RET, obta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM387242(US9938274, 7)
Affinity DataIC50: 17nMAssay Description:Inhibition of MER (unknown origin) using biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 to 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM387242(US9938274, 7)
Affinity DataIC50: 19nMAssay Description:Inhibition of TEK (unknown origin) using biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 to 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM387242(US9938274, 7)
Affinity DataIC50: 32nMAssay Description:Inhibition of AXL (unknown origin) using biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 to 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM387242(US9938274, 7)
Affinity DataIC50: 92nMAssay Description:Inhibition of TYRO3 (unknown origin) using biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 to 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM387242(US9938274, 7)
Affinity DataIC50: 116nMAssay Description:Inhibition of FLT4 (unknown origin) using biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 to 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Nanjing Natinefy Pharmatech

US Patent
LigandPNGBDBM387242(US9938274, 7)
Affinity DataIC50: 198nMAssay Description:Inhibition of KDR (unknown origin) using biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 to 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed