BDBM387248 US9938274, 11

SMILES CCn1cc(-c2ccc(F)cc2)c(=O)c2c(Nc3ccc(Oc4ccnc5cc(OCC(C)(C)O)ccc45)c(F)c3)nccc12

InChI Key InChIKey=VDVXBONJDXIEGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387248   

TargetHepatocyte growth factor receptor(Human)
Nanjing Natinefy Pharmatech

US Patent
LigandPNGBDBM387248(US9938274, 11)
Affinity DataIC50: 9.5nMAssay Description:A study on inhibition of protein kinases activity at in vitro biochemical levelMaterial and method: kinases such as c-Met, VEGFR-2, Axl and RET, obta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Nanjing Natinefy Pharmatech

US Patent
LigandPNGBDBM387248(US9938274, 11)
Affinity DataIC50: 5.00E+3nMAssay Description:A study on inhibition of protein kinases activity at in vitro biochemical levelMaterial and method: kinases such as c-Met, VEGFR-2, Axl and RET, obta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent