BDBM387277 N-(2,6- Difluorophenyl)-5-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol- 3-yl)-2-methoxy- phenyl)thiophene- 2-carboxamide ::US10292981, Example 160
SMILES COc1ccc(cc1-c1ccc(s1)C(=O)Nc1c(F)cccc1F)C1=NOC(C)(C)C1=O
InChI Key InChIKey=ZAKLURTYMKCKHA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 387277
Affinity DataIC50: <1.00E+3nMAssay Description:Jurkat E6.1 cells were seeded at a density of 1-2×105 cells per well in calcium-4 dye prepared in calcium free HBSS (Sigma, USA). Test compounds from...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair