BDBM388299 US10294230, Compound E1-1.3::US10584127, Compound E1-1.3::US11136328, Compound E1-1.3::US11752155, Compound E1-1.3B'

SMILES FC1(F)CN(CC[C@@H]1CNc1nccn2cnnc12)C(=O)OCc1ccc(Cl)cc1

InChI Key InChIKey=ILMWFFHSCLSVNP-UHFFFAOYSA-N

Data  1 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 388299   

TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Rugen Holdings (Cayman)

US Patent
LigandChemical structure of BindingDB Monomer ID 388299BDBM388299(US10294230, Compound E1-1.3 | US10584127, Compound...)
Affinity DataIC50: 1.00E+7nMAssay Description:This example describes an NR2B receptor binding assay in rat brain using [3H] (E)-N1-(2-methoxybenzyl)-cinnamidine (see below). The binding assay met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
US Patent