BDBM389953 2-[1-(4-Chlorophenyl)-1H- pyrrolo[2,3-c]pyridin-2- yl]pyrazine::US10766897, Compound 124::US10968223, Compound 124::US9951068, Compound 124

SMILES Clc1ccc(cc1)-n1c(cc2ccncc12)-c1cnccn1

InChI Key InChIKey=DMBYEPFBOBWEJT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 389953   

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389953(US9951068, Compound 124 | 2-[1-(4-Chlorophenyl)-1H...)
Affinity DataIC50: 50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389953(US9951068, Compound 124 | 2-[1-(4-Chlorophenyl)-1H...)
Affinity DataIC50: 50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389953(US9951068, Compound 124 | 2-[1-(4-Chlorophenyl)-1H...)
Affinity DataIC50: 50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389953(US9951068, Compound 124 | 2-[1-(4-Chlorophenyl)-1H...)
Affinity DataIC50: 50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
US Patent