BDBM389968 5-[1-(4-Chlorophenyl)-1H- pyrrolo[2,3-c]pyridin-2-yl]-N- (oxan-4-yl)pyrimidin-2-amine::US10766897, Compound 139::US10968223, Compound 139::US9951068, Compound 139

SMILES Clc1ccc(cc1)-n1c(cc2ccncc12)-c1cnc(NC2CCOCC2)nc1

InChI Key InChIKey=AIUCZZNOIPJJNM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 389968   

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389968(US9951068, Compound 139 | 5-[1-(4-Chlorophenyl)-1H...)
Affinity DataIC50: 50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389968(US9951068, Compound 139 | 5-[1-(4-Chlorophenyl)-1H...)
Affinity DataIC50: 50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389968(US9951068, Compound 139 | 5-[1-(4-Chlorophenyl)-1H...)
Affinity DataIC50: 50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389968(US9951068, Compound 139 | 5-[1-(4-Chlorophenyl)-1H...)
Affinity DataIC50: 50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
US Patent

LigandPNGBDBM389968(US9951068, Compound 139 | 5-[1-(4-Chlorophenyl)-1H...)
Affinity DataIC50: 550nMAssay Description:Electrophysiological recordings were made from a Chinese Hamster Lung cell line stably expressing the full length hERG channel. Single cell ion curre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
US Patent

LigandPNGBDBM389968(US9951068, Compound 139 | 5-[1-(4-Chlorophenyl)-1H...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
US Patent

LigandPNGBDBM389968(US9951068, Compound 139 | 5-[1-(4-Chlorophenyl)-1H...)
Affinity DataIC50: 550nMAssay Description:hERG: Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent