BDBM390023 4-amino-1-[(3R)-1-[(E)-4-(4- methylpiperazin-1-yl)but-2-enoyl]- 3-piperidyl]-3-(4-phenoxyphenyl)- 6H-pyrrolo[2,3-d]pyridazin-7-one::US10323037, Example 36::US9951077, 36
SMILES CN1CCN(C\C=C\C(=O)N2CCC[C@H](C2)n2cc(-c3ccc(Oc4ccccc4)cc3)c3c(N)n[nH]c(=O)c23)CC1
InChI Key InChIKey=XOPXUXJHCMNSJS-JHEAYKPVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 390023
Affinity DataIC50: <10nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair