BDBM390059 US10323037, Example 72::US9951077, 72

SMILES COc1cc(ccc1Oc1ccc(Cl)c(Cl)c1)-c1cn([C@@H]2CCCN(C2)C(=O)C=C)c2c1c(N)n[nH]c2=O

InChI Key InChIKey=IIHYWYHYLFHPEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390059   

TargetTyrosine-protein kinase BTK(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM390059(US9951077, 72 | US10323037, Example 72)
Affinity DataIC50: 505nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM390059(US9951077, 72 | US10323037, Example 72)
Affinity DataIC50: 505nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
US Patent