BDBM390065 US10323037, Example 78::US9951077, 78

SMILES Nc1n[nH]c(=O)c2n(cc(-c3ccc(Oc4c(F)cccc4Cl)cc3)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=MMZADHOKPXKFTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390065   

TargetTyrosine-protein kinase BTK(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM390065(US9951077, 78 | US10323037, Example 78)
Affinity DataIC50: 10nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM390065(US9951077, 78 | US10323037, Example 78)
Affinity DataIC50: 10nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
US Patent