BDBM390444 US9956192, Compound 10b

SMILES COc1ccccc1N1C(=O)[C@@H](C(C)C)N(Cc2ccc(cc2)C(=O)NO)C1=O

InChI Key InChIKey=AITXGSQUYXQUAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390444   

TargetHistone deacetylase 6(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM390444(US9956192, Compound 10b)
Affinity DataIC50: 22.2nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM390444(US9956192, Compound 10b)
Affinity DataIC50: 1.18E+4nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent