BDBM390753 US9957263, Example 15

SMILES CCS(=O)(=O)Nc1cc(C2CC2)c(Oc2ccc(F)cc2F)c(c1)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key InChIKey=RAGLTXDFRVRTAD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390753   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM390753(US9957263, Example 15)
Affinity DataKi:  2.60nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM390753(US9957263, Example 15)
Affinity DataKi:  4.60nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent