BDBM3914 US8530670, 3

SMILES Fc1cc(F)c(F)c(c1)C1N(C(=O)CC1=O)c1ccc2nc[nH]c2c1

InChI Key InChIKey=ZNAAGVDTDSPPLX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3914   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM3914(US8530670, 3)
Affinity DataKi:  13.9nM ΔG°:  -10.9kcal/mole IC50: 72.5nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2013
Entry Details
US Patent