BDBM391518 2,4-diisopropyl-6-methoxy-8-::US9957268, Example 16

SMILES COc1cc2N(CC(C)C)C(=O)C(Oc2c(c1)-c1cn(C)c(=O)c2[nH]ccc12)C(C)C

InChI Key InChIKey=KIECDOZHTVNIPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391518   

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandPNGBDBM391518(US9957268, Example 16 | 2,4-diisopropyl-6-methoxy-...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4 [42-168](Human)
Incyte

US Patent
LigandPNGBDBM391518(US9957268, Example 16 | 2,4-diisopropyl-6-methoxy-...)
Affinity DataIC50: 550nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent