BDBM391777 6-((7-(3-Chloro-4-cyanophenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)amino)-N-((1r,4r)-4-hydroxycyclohexyl)pyridazine-3-carboxamide::US10300067, Example 29

SMILES N#Cc1ccc(N2CCc3c(ncnc3Nc3ccc(C(=O)N[C@H]4CC[C@H](O)CC4)nn3)C2)cc1Cl

InChI Key InChIKey=FAPCBFLCDQUXTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391777   

TargetAndrogen receptor(Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 391777BDBM391777(US10300067, Example 29 | 6-((7-(3-Chloro-4-cyanoph...)
Affinity DataIC50: 200nMAssay Description:Antagonist activity for AR was evaluated according to the following method. COS-7 cells (ATCC) were transfected with pMMTV-luc vector (reporter plasm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent